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Inventi Rapid - Molecular Pharmacology

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: Molecular Pharmacology’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas in the growing field of molecular pharmacology. It aims to cover the developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, and proteomics.

  • HEPATOPROTECTIVE ACTIVITY OF IGNORED MONOCOT GRASS KYLLINGA TRICEPS ROTTB.
    Amit Upadhyay*, Suman Jain, Neetu Bhalla, Kanika Arora, Subodh Dubey    Download Full Text

    The aim of present study was evaluation of in-vivo hepatoprotective activity of monocot grass Kyllinga triceps rottb. In the present study hepatotoxicity was induced by using CCl4, silymarin was taken as standard drug. Ethanolic and petroleum ether extracts were prepared for study. It was observed that among all the extracts of kyllinga triceps rottb, the petroleum ether extract significantly decr...

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  • COMPARATIVE EVALUATION OF ANTIDIABETIC ACTIVITY OF YESAKA AND METFORMIN IN STREPTOZOTOCIN INDUCED DIABETIC RATS
    Nitin D Deore, Shruti Gupta*, Birendra Shrivastav, C D Upasni, Kishori G Apte, Shaikh A M    Download Full Text

    The present study was performed to evaluate the antihyperglycemic effects of yesaka, an ayurvedic polyherbal formulation and metformin in high fat diet-streptozotocin induced diabetic rats. Diabetes was induced by feeding Sprague Dawley rats with high-fat diet (HFD) for two months followed by a single dose of streptozotocin (STZ, 30 mg/kg intraperitoneally). All the diabetic rats were orally treat...

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  • RENOPROTECTIVE EFFECT OF OMEPRAZOLE IN STREPTOZOTOCIN INDUCED DIABETIC NEPHROPATHY
    Alka Verma*, Rupinder Kaur, Abhishake Chambyal, Ashwani Chandel, Kanchan Wala    Download Full Text

    The present study has been undertaken to investigate the renoprotective effect of omeprazole in streptozotocin-induced diabetic nephropathy in Wistar rats. Diabetic nephropathy was induced with a single injection of streptozotocin (STZ, 45 mg/kg, i.p.). Omeprazole (20 mg/kg; 40 mg/kg, p.o.; 4 weeks) was administered to diabetic rats after 4 weeks of STZ treatment. A battery of biochemical tests su...

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  • ANTIDIABETIC ACTIVITY OF AERIAL PARTS OF TINOSPORA CORDIFOLIA (WILD) AGAINST STZ INDUCED HYPERGLYCEMIA
    Prabhat Kumar Saxena*, D K Sharma, Archana Srivastava    Download Full Text

    The antidiabetic activity of extracts of Tinospora cordifolia (Wild.) aerial parts in different solvents (Pet. Ether, Methanol and Aqueous) was studied on streptozotocin (STZ) induced diabetic albino rats using glibenclamide as standard drug. Bio-chemical estimation of rat was done viz. blood sugar level, glycosylated haemoglobin (HBA1C), C-peptide, triglyceride (TG) and total cholestrol (TC) aft...

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  • ANTIVIRAL MECHANISM OF PHYTOESTROGEN
    Anjali*, Divya Tripathi    Download Full Text

    Phytoestrogens are naturally occurring plant-derived bioactive compounds whose role is to protect plants. These compounds possess several anti-viral properties and are present in fruits and vegetables, nuts and seeds and are commonly consumed by humans. Here we aim to review various anti-viral mechanisms employed by phytoestrogens....

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  • A REVIEW ON QUINIC ACID AND ITS THERAPEUTIC POTENTIAL
    Bhavna Devi, Souravh Bais*, Naresh Singh Gill    Download Full Text

    Phenolics are the large classes of compounds, spread extensively in plant kingdom, especially the secondary metabolites like simple phenol and phenolic acids. Article was designed to explore the therapeutic effect of quinic acid through available literature (last 20 years literature). The last 20 years literatures was carried out by searching bibliographic data bases such as Pubmed, Scopus, Googl...

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