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Inventi Rapid - Molecular Pharmacology

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: Molecular Pharmacology’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas in the growing field of molecular pharmacology. It aims to cover the developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, and proteomics.

  • ETORICOXIB AND ESMOLOL PREVENTS VASCULAR OXIDATIVE STRESS IN RATS TREATED WITH ATHEROGENIC DIET AND TRITON WR1339
    Yash Prashar*, Ritu, Naresh Singh Gill    Download Full Text

    Atherosclerosis is no longer a disease attributed mainly to the high lipid content of the body but has come to be regarded as a chronic inflammatory disease with an autoimmune component. Atherosclerotic plaques occur preferentially in coronary arteries, where shear stress is oscillatory. Triton WR1339 and atherogenic diet causes decrease in shear stress leading to increased free radical production...

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  • A SHORT COMPREHENSIVE AND IMPERATIVE NOTE ON REGENERATIVE PHARMACOLOGY
    Devansh Mehta*, Parkhi Rastogi, Mohd Shuaib, Mohd Ali    Download Full Text

    Pharmacology is the science of drugs, and study of mechanism of action of drugs and lead compounds on the targets or target proteins or receptor molecules. Since ages, pharmacology and pharmaco-therapeutics have emerged and have been contributing to the health sciences and medical industry through its innovation and rigorous hard work in order to find innovative cure and treatment protocols, for ...

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  • A REVIEW ON BIOCHEMICAL MARKERS IN ACUTE CORONARY SYNDROME
    Reshma Nehere, D D Bandawane*    Download Full Text

    Cardiac biomarkers play a crucial role in accurate diagnosis of myocardial necrosis and for assessing risk and directing appropriate therapy that improves clinical outcome. The use of biomarkers in basic and clinical research as well as in clinical practice has become so common. The earliest biomarkers such as alanine aminotransferase and lactate dehydrogenase have fallen out of use with the devel...

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  • HEPATOPROTECTIVE ACTIVITY OF IGNORED MONOCOT GRASS KYLLINGA TRICEPS ROTTB.
    Amit Upadhyay*, Suman Jain, Neetu Bhalla, Kanika Arora, Subodh Dubey    Download Full Text

    The aim of present study was evaluation of in-vivo hepatoprotective activity of monocot grass Kyllinga triceps rottb. In the present study hepatotoxicity was induced by using CCl4, silymarin was taken as standard drug. Ethanolic and petroleum ether extracts were prepared for study. It was observed that among all the extracts of kyllinga triceps rottb, the petroleum ether extract significantly decr...

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  • RENOPROTECTIVE EFFECT OF OMEPRAZOLE IN STREPTOZOTOCIN INDUCED DIABETIC NEPHROPATHY
    Alka Verma*, Rupinder Kaur, Abhishake Chambyal, Ashwani Chandel, Kanchan Wala    Download Full Text

    The present study has been undertaken to investigate the renoprotective effect of omeprazole in streptozotocin-induced diabetic nephropathy in Wistar rats. Diabetic nephropathy was induced with a single injection of streptozotocin (STZ, 45 mg/kg, i.p.). Omeprazole (20 mg/kg; 40 mg/kg, p.o.; 4 weeks) was administered to diabetic rats after 4 weeks of STZ treatment. A battery of biochemical tests su...

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  • ANTIDIABETIC ACTIVITY OF AERIAL PARTS OF TINOSPORA CORDIFOLIA (WILD) AGAINST STZ INDUCED HYPERGLYCEMIA
    Prabhat Kumar Saxena*, D K Sharma, Archana Srivastava    Download Full Text

    The antidiabetic activity of extracts of Tinospora cordifolia (Wild.) aerial parts in different solvents (Pet. Ether, Methanol and Aqueous) was studied on streptozotocin (STZ) induced diabetic albino rats using glibenclamide as standard drug. Bio-chemical estimation of rat was done viz. blood sugar level, glycosylated haemoglobin (HBA1C), C-peptide, triglyceride (TG) and total cholestrol (TC) aft...

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