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Inventi Rapid - NDDS

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    Journal Scope:

    Quarterly published in print and online ‘Inventi Rapid/Impact: NDDS’ publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. The journal covers all the areas under novel drug delivery systems. It welcomes articles pertaining to nano drug delivery systems; gastroretensive system, colonic drug delivery, bioadhesive and mucoadhesive systems; nasopulmonary drug delivery; ocular delivery; transdermal delivery, implants and inserts; protein and peptide delivery; manufacturing, quality control and regulatory aspects of NDDS, etc.

  • FORMULATION AND EVALUATION OF BUCCAL MUCOADHESIVE PATCHES FOR THE TREATMENT OF HYPERTENSION
    Shiva Kumar Yellanki*, Uday Kumar K, Teelavath Mangilal, M Ravi Kumar    Download Full Text

    Nimodipine is dihydropyridine calcium channel blocker, generally used for the treatment of high blood pressure. It has shown the good results in preventing major issues of subarachnoid hemorrhage (a form of cerebral hemorrhage) termed vasospasm; this is currently the main use of nimodipine. In the present study buccal drug delivery of nimodipine was developed. Matrix type of buccal patches was dev...

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  • WHY? VAGINAL DRUG DELIVERY SYSTEM FOR PROGESTERONE AND ESTROGEN
    B Senthilnathan*, G Nimitha Devi, R B Balakrishna, M Vigneshwar, R Manisha    Download Full Text

    Vaginal route is one of the underutilized route of administration which is known since ancient time, but nowadays it is gaining importance because of advanced formulation technologies which include effervescent technology, Bio-adhesive technology and vaginal rings. Vaginal route remains a promising route when the drug undergoes gastric disintegration (Progesterone) and hepatic first pass (Estrogen...

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  • RELEASE MODULATING HYDROPHILIC MATRIX SYSTEMS OF NIFEDIPINE EXTENDED RELEASE TABLETS: OPTIMIZATION OF FORMULATION USING 32 FULL FACTORIAL DESIGN
    Oza Nishant A*, Satyajit Sahoo, Gandhi Pooja    Download Full Text

    The objective of the present research work was to systemically device a model of nifedipine extended release tablet and optimization of drug release according to the U.S.P. In this study, the nifedipine extended release tablet were formulated using polymer HPMC K4M and HPMC K100M by wet granulation method and HPMC K4M was also added extra granularly. These formulations were evaluated for the param...

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  • DEVELOPMENT OF MICELLES FORMULATION FOR ORAL DRUG DELIVERY OF NORFLOXACIN
    Kanade Rahul Rajendra*, Sadaphule Sourabh Ashok, Ansari A M, Padwal Pooja Vijaykumar, Patil Daridevanand Baburao    Download Full Text

    Many drugs have poor water solubility and for oral delivery of such drugs are usually associated with limitation of low bioavailability. Develop a stable micellar formulation for poorly water soluble drugs having an excellent capacity to increase solubilization and bioavailability. The aim of study was to develop micelles formulation for oral delivery of norfloxacin. Developed micelle contains a l...

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  • FORMULATION AND EVALUATION OF EMULGEL OF CAPSICUM FRUTESCENCE EXTRACT
    Yogesh S Thorat*, Madhuri Pandurang Alte, Hosmani Avinash H, Akshay Sudhakar Dhupad, Pooja Vijaykumar Padwal    Download Full Text

    Capsaicin is the most abundant of capsaicinoid which is the pungent metabolite in the fruits of Capsicum species. Capsaicinoid is responsible for about 90% of total pungency in the fruit. Capsaicin has been used as a topical analgesic against rheumatoid arthritis pain and inflammation. The aim of the proposed research work was to formulate microemulsion incorporating chilli extract for topical the...

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  • FORMULATION DEVELOPMENT AND EVALUATION OF TOPICAL BIOADHESIVE GEL BY USING 3 LEVEL FACTORIAL DESIGN
    Vijay Krishnarao Patil*, Harshala Motiram Chachare    Download Full Text

    The aim of present work was to develop a topical bioadhesive gel of lornoxicam by using three level factorial design and evaluate the effects of two independent variables {amount of carbopol (934 = X1) and sodium carboxymethylcellulose (NaCMC) = X2)} on the dependent variable (bioadhesiveness, viscosity and in-vitro drug release). In the present research work, the different concentration of polyme...

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